PKRRATING SECRETS

3B). R526 within the loop in between αJ and αI anchors the C-terminal percentage of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the main chain carbonyl of R413. The idea from the activation section is stabilized by a hydrogen bond among Y454 and E480 from αF. m